Table 1 Baseline clinicopathologic characteristics of the 72 patients with unresectable local advance sigmoid colon cancer (LASCC)
Characteristic | No. (%) | |
|---|---|---|
Age | ||
≤ 65 | 58 (80.6) | |
> 65 | 14 (19.4) | |
Gender | ||
Male | 54 (75.0) | |
Female | 18 (25.0) | |
cT stage | ||
T3 | 9 (12.5) | |
T4a | 5 (6.9) | |
T4b | 58 (80.6) | |
cN stage | ||
N0 | 1 (1.4) | |
N1 | 25 (34.7) | |
N2 | 46 (63.9) | |
Clinical stage | ||
IIc | 1 (1.4) | |
IIIb | 15 (20.8) | |
IIIc | 55 (76.4) | |
IV | 1 (1.4) | |
Tumor differentiation | ||
High | 15 (20.8) | |
Moderate | 54 (75.0) | |
Low | 3 (4.2) | |
Involved organ | ||
Bladder | 45 (62.5) | |
Ureter | 8 (11.1) | |
Abdominal/Pelvic wall | 18 (25.0) | |
Small intestine | 9 (12.5) | |
CEA | ||
≤ 5 ng/ml | 30 (41.7) | |
> 5 ng/ml | 35 (48.6) | |
Unknown | 7 (9.7) | |
Bladder fistula/perforation | ||
Yes | 14 (19.4) | |
No | 58 (80.6) | |
Intestinal obstruction | ||
Yes | 13 (18.1) | |
No | 59 (81.9) | |
Family history | ||
Yes | 12 (16.7) | |
No | 60 (83.3) | |
MMR | ||
dMMR | 6 (8.3) | |
pMMR | 40 (55.6) | |
Unknown | 26 (36.1) | |
KPS | ||
≥ 90 | 58 (80.6) | |
< 90 | 14 (19.4) | |