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Table 3 Variables associated with ME extent in multivariate linear regression model

From: Determining optimal clinical target volume margins in high-grade glioma based on microscopic tumor extension and magnetic resonance imaging

Variable

β

SE

95% CI for β

P value

Score (0, 1)

Pathologic grade

0.513

0.136

0.232–0.794

0.001

 

 Grade III

    

0

 Grade IV

    

1

SVZ contact

0.380

0.124

0.125–0.635

0.005

 

 No

    

0

 Yes

    

1

Molecular markers

     

 MGMT methylation status

0.439

0.129

0.171–0.706

0.002

 

  Unmethylated

    

0

  Methylated

    

1

 IDH mutation status

0.320

0.141

0.028–0.611

0.033

 

  Mutated

    

0

  Wild type

    

1

 1p/19q co-deletion status

0.333

0.120

0.084–0.581

0.011

 

  Co-deleted

    

0

  Non-co-deleted

    

1

  1. ME microscopic extension; β regression coefficient; SE standard error; CI confidence interval; SVZ subventricular zone; MGMT O6-methylguanine-DNA-methyltransferase; IDH isocitrate dehydrogenase; 1p/19q co-deletion the co-deletion of chromosome arms 1p and 19q
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Radiation Oncology

ISSN: 1748-717X

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