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Table 3 Variables associated with ME extent in multivariate linear regression model

From: Determining optimal clinical target volume margins in high-grade glioma based on microscopic tumor extension and magnetic resonance imaging

Variable β SE 95% CI for β P value Score (0, 1)
Pathologic grade 0.513 0.136 0.232–0.794 0.001  
 Grade III      0
 Grade IV      1
SVZ contact 0.380 0.124 0.125–0.635 0.005  
 No      0
 Yes      1
Molecular markers      
 MGMT methylation status 0.439 0.129 0.171–0.706 0.002  
  Unmethylated      0
  Methylated      1
 IDH mutation status 0.320 0.141 0.028–0.611 0.033  
  Mutated      0
  Wild type      1
 1p/19q co-deletion status 0.333 0.120 0.084–0.581 0.011  
  Co-deleted      0
  Non-co-deleted      1
  1. ME microscopic extension; β regression coefficient; SE standard error; CI confidence interval; SVZ subventricular zone; MGMT O6-methylguanine-DNA-methyltransferase; IDH isocitrate dehydrogenase; 1p/19q co-deletion the co-deletion of chromosome arms 1p and 19q