Fig. 1From: Determining optimal clinical target volume margins in high-grade glioma based on microscopic tumor extension and magnetic resonance imagingTumor microscopic extension distribution for different locations based on preoperative T1-weighted MRI. a, d, g Type I; b, e, h Type II; c, f, i Type III. At the sites where the glioma cells produced direct invasion, perineural spread, subpial growth and perivascular spread are outlined in red, yellow, brown and blue, respectively. Black line: tumor-containing area; blue line: PTBE-containing area; green line: 0.25 cm intervals. S skull; V ventricle; F falxBack to article page