Skip to main content

Table 4 Radiogenic side effects at the end of RT under DIBH and 3 months or 1 year thereafter

From: Deep-inspirational breath-hold (DIBH) technique in left-sided breast cancer: various aspects of clinical utility

Grade

Acute dermatitis (n = 43)

3 months after RT (n = 43)

12 months after RT (n = 35)

Pneumonitis

Dermatitis

Breast fibrosis

Pneumonitis

Dermatitis

Breast fibrosis

(A)

       

0

3

41

14

26

35

30

29

1

33

2

29

15

0

5

4

2

7

0

0

2

0

0

2

  

3 months after RT

p (ANOVA)

12 months after RT

p (ANOVA)

  

n (%)

MLDC

n (%)

MLDC

(B)

       

3DCRT + DIBH

visual score 0

6 (14.0)

12.0 ± 38.4

 < 0.001

8 (22.9)

37.3 ± 83.1

0.119

Visual score 1

20 (46.5)

49.4 ± 41.4

15 (42.9)

49.6 ± 30.6

Visual score 2

17 (39.5)

126.4 ± 54.9

12 (34.2)

95.7 ± 92.5

3DCRT + FB

visual score 0

7 (28.0)

32.4 ± 32.6

0.035

6 (40.0)

20.3 ± 53.5

0.522

Visual score 1

11 (44.0)

43.1 ± 19.3

6 (40.0)

33.5 ± 21.8

Visual score 2

7/25 (28.0)

71.4 ± 32.1

3 (20.0)

53.7 ± 37.8

  1. MLDC: mean lung density changes
  2. A, Toxicity was assessed according to the CTC AE vs. 4 system
  3. B, Lung density changes by means of visual assessment and lung density measurements were compared to the same parameters of a historical cohort of patients having received WBI in the supine position under FB in 2012; no significant difference was found