Deep-inspirational breath-hold (DIBH) technique in left-sided breast cancer: various aspects of clinical utility

Radiation Oncology

Table 1 Dosimetry data among patients treated with 3DCRT and DIBH

n = 88	WBI (n = 54)							WBI + nodal/PM RT (n = 34)
	FB (1)	DIBH (2)	Prone (3)	p	p (post hoc tests)			FB	DIBH	p
	FB (1)	DIBH (2)	Prone (3)	p	1 vs 2	1 vs 3	2 vs 3	FB	DIBH	p
PTV HI	0.102 ± 0.017	0.101 ± 0.012	0.105 ± 0.012	0.214	0.362	0.381	0.067	0.122 ± 0.011	0.129 ± 0.013	0.215
Heart mean dose (Gy)	3.16 ± 1.58	1.38 ± 0.37	2.02 ± 1.15	< 0.001	< 0.001	< 0.001	< 0.001	4.87 ± 1.21	2.13 ± 0.57	< 0.001
Heart V25 Gy (%)	4.13 ± 3.13	0.46 ± 0.51	1.44 ± 2.21	< 0.001	< 0.001	< 0.001	0.009	6.42 ± 2.43	1.23 ± 0.91	< 0.001
LAD mean dose (Gy)	13.05 ± 8.30	4.55 ± 1.95	9.98 ± 7.16	< 0.001	< 0.001	0.098	< 0.001	18.95 ± 7.03	7.47 ± 4.39	< 0.001
LAD max dose (Gy)	39.81 ± 14.52	18.92 ± 12.86	31.99 ± 14.15	< 0.001	< 0.001	0.021	< 0.001	47.03 ± 7.56	31.86 ± 10.83	< 0.001
Ipsilateral lung mean dose (Gy)	7.01 ± 1.97	6.37 ± 1.44	0.90 ± 0.63	< 0.001	< 0.001	< 0.001	< 0.001	14.29 ± 2.32	11.29 ± 1.91	< 0.001
Ipsilateral lung V20Gy (%)	12.11 ± 4.31	10.65 ± 3.17	0.65 ± 1.14	< 0.001	< 0.001	< 0.001	< 0.001	28.66 ± 5.36	21.64 ± 4.64	< 0.001
Contralateral breast mean dose (Gy)	0.36 ± 0.34	0.46 ± 0.50	0.59 ± 0.54	0.084	0.098	0.033	0.261	1.45 ± 1.31	1.4 ± 1.07	0.755
Contralateral breast V10 Gy (%)	0.46 ± 0.99	0.82 ± 1.59	0.76 ± 1.31	0.435	0.172	0.287	0.873	2.89 ± 3.32	3.07 ± 3.38	0.685

ISSN: 1748-717X