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Table 2 Median total doses for dose escalation of PET-positive local recurrence and pelvic lymph nodes and median total dose for oligometastatic bone lesions

From: A survey among German-speaking radiation oncologists on PET-based radiotherapy of prostate cancer

 

Median total dose in EQD2(1.5 Gy) [Gy]

Median single dose [Gy]

RT technique

PET-positive local recurrence

70.00 (range: 56.89–85.71)

2.00 (range: 1.80–4.30)

SQB: 24.4% (21/86)

   

SIB: 66.3% (57/86)

   

No boost: 2.3% (2/86)

   

Other: 7.0% (6/86), one with LDR-brachytherapy with 108 Gy

PET-positive pelvic LNs

62.00 (range: 52.61–80.00)

2.00 (range: 1.80–2.60)

SQB: 19.8% (13/84)

   

SIB: 75.6% (65/84)

   

No boost: 3.5% (3/86)

   

Other: 1.2% (1/86) with a SBRT boost

Oligometastatic bone lesions

64.64 (range: 31.43–197.14)

5.00 (range: 1.80–20.00)

CRT: 51.4% (56/109)

   

SBRT: 43.1% (47/109)

   

No RT: 5.5% (6/109)

  1. RT radiotherapy, LN lymph nodes, EQD2(1.5 Gy) equivalent dose at fractionation of 2 Gy with α/β = 1.5 Gy, SQB sequential boost, SIB simultaneous integrated boost, LDR low dose rate, SBRT stereotactic body radiotherapy, CRT conventional fractionated radiotherapy