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Table 3 Mean institutional dose distributions and dose requirements of the EORTC 1420 protocol for the different volumes

From: Quality assurance of radiotherapy in the ongoing EORTC 1420 “Best of” trial for early stage oropharyngeal, supraglottic and hypopharyngeal carcinoma: results of the benchmark case procedure

Volumes Mean institutional doses (SD) Dose requirements given by the EORTC 1420 Protocol
Planning organ-at-risk volume of the brainstem Dmax = 19.96 (9.12) Dmax < 35 Gy
Cervical esophagus Dmean = 14.75 (5.43) Dmean < 30 Gy
Contralateral parotid Dmean = 5.53 (1.79) Dmean < 5–10 Gy
Cricoid pharyngeal inlet D2% = 47.34 (6.98) D2% < 66 Gy
Contralateral sub-mandibular gland Dmean = 7.82 (1.67) Dmean < 10 Gy
Extended oral cavity-PTV Dmean = 27.54 (4.66) Dmean < 30–35 Gy
Glottis Dmean = 16.26 (3.56) Dmean < 20 Gy
Ipsilateral parotid Dmean = 25.60 (5.83) Dmean < 30–35 Gy
Mandible D2% = 56.92 (4.59) D2% < 66 Gy
Pharyngeal constrictor muscles Dmean = 33.75 (3.95) Dmean < 30–40 Gy
Prophylactic PTV D95% = 52.91 (0.81) D95% > 51.7 Gy
Therapeutic PTV D95% = 63.89 Gy (1.04) D95% > 62.7 Gy
Planning organ-at-risk volume of the spinal cord Dmax = 36.95 (4.05) Dmax < 40 Gy
Supraglottic larynx Dmean = 23.56 (4.90) Dmean < 45–50 Gy
Thyroid gland Dmean = 23.26 (2.05) Dmean < 25 Gy