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Table 3 Mean institutional dose distributions and dose requirements of the EORTC 1420 protocol for the different volumes

From: Quality assurance of radiotherapy in the ongoing EORTC 1420 “Best of” trial for early stage oropharyngeal, supraglottic and hypopharyngeal carcinoma: results of the benchmark case procedure

Volumes

Mean institutional doses (SD)

Dose requirements given by the EORTC 1420 Protocol

Planning organ-at-risk volume of the brainstem

Dmax = 19.96 (9.12)

Dmax < 35 Gy

Cervical esophagus

Dmean = 14.75 (5.43)

Dmean < 30 Gy

Contralateral parotid

Dmean = 5.53 (1.79)

Dmean < 5–10 Gy

Cricoid pharyngeal inlet

D2% = 47.34 (6.98)

D2% < 66 Gy

Contralateral sub-mandibular gland

Dmean = 7.82 (1.67)

Dmean < 10 Gy

Extended oral cavity-PTV

Dmean = 27.54 (4.66)

Dmean < 30–35 Gy

Glottis

Dmean = 16.26 (3.56)

Dmean < 20 Gy

Ipsilateral parotid

Dmean = 25.60 (5.83)

Dmean < 30–35 Gy

Mandible

D2% = 56.92 (4.59)

D2% < 66 Gy

Pharyngeal constrictor muscles

Dmean = 33.75 (3.95)

Dmean < 30–40 Gy

Prophylactic PTV

D95% = 52.91 (0.81)

D95% > 51.7 Gy

Therapeutic PTV

D95% = 63.89 Gy (1.04)

D95% > 62.7 Gy

Planning organ-at-risk volume of the spinal cord

Dmax = 36.95 (4.05)

Dmax < 40 Gy

Supraglottic larynx

Dmean = 23.56 (4.90)

Dmean < 45–50 Gy

Thyroid gland

Dmean = 23.26 (2.05)

Dmean < 25 Gy