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Table 4 DVH parameters from 40 patients versus the LEM constraints

From: Conversion and validation of rectal constraints for prostate carcinoma receiving hypofractionated carbon-ion radiotherapy with a local effect model

Constraints (16fx)

aLEM constraints

bDVH summary

cMedian

dMaximum

Our previous study

D20% ≤ 43.14

37.91

e49.96

 

D10% ≤ 58.48

53.53

f62.12

 

D5% ≤ 65.11

59.96

65.18

 

D0% ≤ 68.33

62.91

66.61

CNAO’s study

D10cc ≤ 54.00

37.58

53.52

 

D5cc ≤ 61.00

53.43

60.30

 

D1cc ≤ 66.00

62.54

65.86

Constraints (12fx)

gLEM Constraints

Patient 1

Patient 2

Constraints from MKM LQ

D20% ≤ 37.60

24.27

30.53

 

D10% ≤ 49.74

38.65

46.75

 

D5% ≤ 55.27

46.45

52.86

 

D0% ≤ 58.01

54.11

55.37

 

D10cc ≤ 45.97

29.89

27.10

 

D5cc ≤ 51.70

42.17

44.55

 

D1cc ≤ 55.97

53.20

54.80

  1. aLEM rectum constraints for 16-fraction CIRT, the percentage volume constraints were from our previous study, the absolute volume constraints were from CNAO [Gy (RBE)]
  2. bThe value of D20%, D10%, D5%, D0%, D10cc, D5cc, and D1cc parameters processed from each patient’ rectum DVH of 38 patients who received 16-fraction CIRT and 2 patients who received 12-fraction CIRT [Gy (RBE)]
  3. cThe median value of DVH parameters among the 16-fraciton group and 12-fraction group [Gy (RBE)]
  4. dThe maximum value of DVH parameters among the 16-fraciton group and 12-fraction group [Gy (RBE)]
  5. eEight patients were over the D20% constraints for 16-fraction CIRT
  6. fFour out of 8 patients were over the D10% constraints for 16-fraction CIRT
  7. gThe LEM rectum constraints converted from MKM LQ strategy for 12-fraction CIRT