From: Split-VMAT technique to control the deep inspiration breath hold time for breast cancer radiotherapy
Structure | Objective/constraint | 8paVMAT | 4paVMAT | p value |
---|---|---|---|---|
PTV breast D90% (Gy) | Constraint ≥ 38.05 | 38.9 ± 0.17 [38.7–39.2] | 38.9 ± 0.18 [38.7–39.3] | 0.17 |
PTV breast CI | – | 0.61 ± 0.10 [0.45–0.76] | 0.60 ± 0.10 [0.43–0.71] | 0.10 |
PTV IMN V32Gy (%) | Constraint ≥ 90 | 95.6 ± 2.46 [91.4–100] | 96.4 ± 1.99 [93.8–100] | 0.41 |
PTV IMN V36Gy (%) | Objective ≥ 90 | 78.8 ± 10.4 [60–96.6] | 84.2 ± 5.7 [77.5–97.4] | 0.037 |
PTV LN V36Gy (%) | Constraint ≥ 90 | 95.9 ± 3.03 [91.8–99.4] | 97.5 ± 1.79 [93.6–99.6] | 0.20 |
Heart DMean (Gy) | Objective ≤ 4 | 2.8 ± 0.9 [1.55–4.6] | 2.9 ± 0.9 [1.8–4.6] | 0.92 |
Heart V5Gy (%) | Objective ≤ 10 | 9.6 ± 3.4 [3.3–17.1] | 9.8 ± 3.3 [3.2–16.6] | 0.72 |
Heart V17Gy (%) | Constraint ≤ 10 | 2.4 ± 2.5 [0.0–7.6] | 2.6 ± 2.5 [0.0–8.0] | 0.06 |
Ipsilateral Lung V17Gy (%) | Constraint ≤ 35 | 25.2 ± 3.4 [18.6–29.2] | 25.3 ± 3.8 [17.7–30] | 0.68 |
Lungs DMean (Gy) | Objective ≤ 6 | 5.9 ± 0.6 [4.7–6.5] | 5.8 ± 0.4 [5.1–6.4] | 0.16 |
C. Lung V5Gy (%) | – | 3.6 ± 2.1 [1.5–7.7] | 2.4 ± 2.0 [0.3–6.2] | 0.024 |
C. Breast DMean (Gy) | Objective ≤ 3.5 | 3.6 ± 0.7 [1.9–4.7] | 3.0 ± 0.7 [1.5–4.0] | ≤ 0.01 |
Humeral head PRV V30Gy (%) | Objective ≤ 2 | 6.3 ± 6.9 [0.0–21.2] | 8.1 ± 9.1 [0.0–26.3] | 0.15 |
Body V5Gy (cc) | – | 5376 ± 1241 [3359.6–7400] | 5396.9 ± 1301.2 [3153.5–7485] | 0.96 |