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Table 3 Dosimetric parameters results obtained for 8paVMAT and 4paVMAT (data are shown as mean values with one standard deviation, and range between brackets)

From: Split-VMAT technique to control the deep inspiration breath hold time for breast cancer radiotherapy

Structure

Objective/constraint

8paVMAT

4paVMAT

p value

PTV breast D90% (Gy)

Constraint ≥ 38.05

38.9 ± 0.17 [38.7–39.2]

38.9 ± 0.18 [38.7–39.3]

0.17

PTV breast CI

0.61 ± 0.10 [0.45–0.76]

0.60 ± 0.10 [0.43–0.71]

0.10

PTV IMN V32Gy (%)

Constraint ≥ 90

95.6 ± 2.46 [91.4–100]

96.4 ± 1.99 [93.8–100]

0.41

PTV IMN V36Gy (%)

Objective ≥ 90

78.8 ± 10.4 [60–96.6]

84.2 ± 5.7 [77.5–97.4]

0.037

PTV LN V36Gy (%)

Constraint ≥ 90

95.9 ± 3.03 [91.8–99.4]

97.5 ± 1.79 [93.6–99.6]

0.20

Heart DMean (Gy)

Objective ≤ 4

2.8 ± 0.9 [1.55–4.6]

2.9 ± 0.9 [1.8–4.6]

0.92

Heart V5Gy (%)

Objective ≤ 10

9.6 ± 3.4 [3.3–17.1]

9.8 ± 3.3 [3.2–16.6]

0.72

Heart V17Gy (%)

Constraint ≤ 10

2.4 ± 2.5 [0.0–7.6]

2.6 ± 2.5 [0.0–8.0]

0.06

Ipsilateral Lung V17Gy (%)

Constraint ≤ 35

25.2 ± 3.4 [18.6–29.2]

25.3 ± 3.8 [17.7–30]

0.68

Lungs DMean (Gy)

Objective ≤ 6

5.9 ± 0.6 [4.7–6.5]

5.8 ± 0.4 [5.1–6.4]

0.16

C. Lung V5Gy (%)

3.6 ± 2.1 [1.5–7.7]

2.4 ± 2.0 [0.3–6.2]

0.024

C. Breast DMean (Gy)

Objective ≤ 3.5

3.6 ± 0.7 [1.9–4.7]

3.0 ± 0.7 [1.5–4.0]

≤  0.01

Humeral head PRV V30Gy (%)

Objective ≤ 2

6.3 ± 6.9 [0.0–21.2]

8.1 ± 9.1 [0.0–26.3]

0.15

Body V5Gy (cc)

5376 ± 1241 [3359.6–7400]

5396.9 ± 1301.2 [3153.5–7485]

0.96

  1. Italic emphasis reflects the significant results
  2. PRV—planning organ at risk volume, CI—conformity index, C. Breast—contralateral breast, C. Lung—contralateral lung