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Table 3 Dose volume histogram characteristics

From: Correction to: Correlation of dosimetric factors with the development of symptomatic radiation pneumonitis in stereotactic body radiotherapy

Characteristic

No radiation pneumonitis (n = 85)

Symptomatic radiation pneumonitis (n = 8)

p value

Contralateral lung V5, %

  

0.05

 Median

3.1%

7.4%

 

 Range

0.0–33.6%

4.2–53.4%

 

Ipsilateral lung V30, %

  

0.001

 Median

3.3%

9.6%

 

 Range

0.8–11.6%

6.5–12.8%

 

Ipsilateral lung V40, %

  

0.003

 Median

2.1%

5.8%

 

 Range

0.5–8.1%

3.6–8.8%

 

Total lung V5, %

  

0.001

 Median

14.7%

29.1%

 

 Range

4.2–46.9%

18.2–56.9%

 

Total lung V10, %

  

0.001

 Median

8.4%

21.7%

 

 Range

2.2–34.6%

10.8–38.4%

 

MVLS from 12.4 Gy, cm3

  

0.31

 Median

3172 cm3

2132 cm3

 

 Range

969–6807 cm3

1439–3592 cm3

 

MVLS from 13.5 Gy, cm3

  

0.31

 Median

3196 cm3

2157 cm3

 

 Range

980–6829 cm3

1452–3603 cm3

 

Total lung V15, %

  

0.001

 Median

5.4%

13.2%

 

 Range

1.2–25.8%

7.8–18.8%

 

Total lung V20, %

  

0.001

 Median

3.4%

9.1%

 

 Range

0.8–19.4%

5.3–12.8%

 

Total lung V25, %

  

0.001

 Median

2.4%

6.7%

 

 Range

0.6–15.2%

3.6–9.6%

 

Total lung V30, %

  

0.002

 Median

1.8%

5.1%

 

 Range

0.5–12.1%

2.4–7.4%

 

Total lung V40, %

  

0.003

 Median

1.1%

3.3%

 

 Range

0.3–8.6%

1.1–4.7%

 
  1. Abbreviations: Vdose is the percent of lung receiving greater than the “dose” (in Gy). Symptomatic Radiation Pneumonitis = RTOG G3 + or CTCAE G2 + RP. MVLS = Minimum Volume of Lung Spared
  2. p values from Wilcoxon Rank Sum tests, with all values Bonferroni adjusted. Bolded p values indicate statistical significance