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Table 3 Dose volume histogram characteristics

From: Correction to: Correlation of dosimetric factors with the development of symptomatic radiation pneumonitis in stereotactic body radiotherapy

Characteristic No radiation pneumonitis (n = 85) Symptomatic radiation pneumonitis (n = 8) p value
Contralateral lung V5, %    0.05
 Median 3.1% 7.4%  
 Range 0.0–33.6% 4.2–53.4%  
Ipsilateral lung V30, %    0.001
 Median 3.3% 9.6%  
 Range 0.8–11.6% 6.5–12.8%  
Ipsilateral lung V40, %    0.003
 Median 2.1% 5.8%  
 Range 0.5–8.1% 3.6–8.8%  
Total lung V5, %    0.001
 Median 14.7% 29.1%  
 Range 4.2–46.9% 18.2–56.9%  
Total lung V10, %    0.001
 Median 8.4% 21.7%  
 Range 2.2–34.6% 10.8–38.4%  
MVLS from 12.4 Gy, cm3    0.31
 Median 3172 cm3 2132 cm3  
 Range 969–6807 cm3 1439–3592 cm3  
MVLS from 13.5 Gy, cm3    0.31
 Median 3196 cm3 2157 cm3  
 Range 980–6829 cm3 1452–3603 cm3  
Total lung V15, %    0.001
 Median 5.4% 13.2%  
 Range 1.2–25.8% 7.8–18.8%  
Total lung V20, %    0.001
 Median 3.4% 9.1%  
 Range 0.8–19.4% 5.3–12.8%  
Total lung V25, %    0.001
 Median 2.4% 6.7%  
 Range 0.6–15.2% 3.6–9.6%  
Total lung V30, %    0.002
 Median 1.8% 5.1%  
 Range 0.5–12.1% 2.4–7.4%  
Total lung V40, %    0.003
 Median 1.1% 3.3%  
 Range 0.3–8.6% 1.1–4.7%  
  1. Abbreviations: Vdose is the percent of lung receiving greater than the “dose” (in Gy). Symptomatic Radiation Pneumonitis = RTOG G3 + or CTCAE G2 + RP. MVLS = Minimum Volume of Lung Spared
  2. p values from Wilcoxon Rank Sum tests, with all values Bonferroni adjusted. Bolded p values indicate statistical significance