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Table 3 Association between patient, disease, and dose characteristics, and patient-reported dizziness

From: Vestibular dose correlates with dizziness after radiosurgery for the treatment of vestibular schwannoma

Parameter

Univariate variables

Multivariate model

OR (95% CI)

p value

OR (95% CI)

p value

Age in years (> 65 vs ≤ 65)

1.12 (0.32–3.90)

0.85

  

Location (intra- vs extra-canalicular)

2.10 (0.46–9.64)

0.33

  

Cystic component (yes vs no)

1.10 (0.24–5.04)

0.89

  

Target volume (> vs ≤ 6.1 cm3)

4.85 (1.43–16.49)

0.01

2.84 (0.53–15.04)

0.21

Target minimum dose

0.85 (0.27–2.67)

0.80

  

Target mean dose

0.72 (0.23–2.24)

0.57

  

Target maximum dose

0.51 (0.16–1.61)

0.25

  

Pre-SRS tumor growth (yes vs no)

2.02 (0.56–7.31)

0.28

  

Koos grade (III–IV vs I–II)

3.45 (1.01–11.81)

0.04

2.41 (0.41–14.24)

0.33

Pre-SRS tinnitus (yes vs no)

1.33 (0.38–4.67)

0.65

  

Pre-SRS dizziness (yes vs no)

3.98 (1.19–13.24)

0.02

4.15 (1.00–17.20)

0.05

Vestibule minimum dose

1.55 (1.03–2.32)

0.03

1.75 (1.05–2.89)

0.02

Vestibule mean dose

1.10 (0.89–1.35)

0.35

  

Vestibule maximum dose

1.01 (0.86–1.19)

0.82

  

Transient volume expansion (yes vs no)

1.96 (0.58–6.61)

0.27

  

Novalis vs Cyberknife

0.47 (0.14–1.55)

0.21

  
  1. Values in bold statistically significant
  2. CI confidence interval, OR odds ratio, SRS stereotactic radiosurgery