|
Time of onset of morphological and/or neurological alterations [days after irradiation]
|
---|
BMC
|
CA v
|
CA d
|
Edema
|
CA
|
Syrinx
|
P I
|
P II
|
---|
Photons
|
108 ± 47
|
107 ± 29
|
149 ± 32
|
194 ± 17
|
198 ± 18b
|
206 ± 23a
|
199 ± 22a
|
212 ± 21
|
12C-ions
|
84 ± 24
|
88 ± 18
|
81 ± 13
|
122 ± 10
|
125 ± 10c
|
124 ± 5
|
129 ± 7
|
137 ± 11
|
- Bold printed latency times are significantly different (p < 0.001) between photon and carbon ion irradiated animals
- BMC bone marrow conversion, CA v/d contrast agent enhancement in the ventral/dorsal musculature outside the spinal cord, respectively, CA contrast agent enhancement inside the spinal cord, P I (paresis I) at least one forelimb showed signs of neurological dysfunction, P II (paresis II) both forelimbs showed signs of paralysis
- a7 out of 8 rats
- b3 out of 7 animals showed CA without paresis I
- c5 out of 8 animals showed CA without paresis II