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Table 1 Mean latency times (± standard deviation) of morphological alterations and neurological distortions after photon and carbon ion irradiation

From: Longitudinal MRI study after carbon ion and photon irradiation: shorter latency time for myelopathy is not associated with differential morphological changes

 

Time of onset of morphological and/or neurological alterations [days after irradiation]

BMC

CA v

CA d

Edema

CA

Syrinx

P I

P II

Photons

108 ± 47

107 ± 29

149 ± 32

194 ± 17

198 ± 18b

206 ± 23a

199 ± 22a

212 ± 21

12C-ions

84 ± 24

88 ± 18

81 ± 13

122 ± 10

125 ± 10c

124 ± 5

129 ± 7

137 ± 11

  1. Bold printed latency times are significantly different (p < 0.001) between photon and carbon ion irradiated animals
  2. BMC bone marrow conversion, CA v/d contrast agent enhancement in the ventral/dorsal musculature outside the spinal cord, respectively, CA contrast agent enhancement inside the spinal cord, P I (paresis I) at least one forelimb showed signs of neurological dysfunction, P II (paresis II) both forelimbs showed signs of paralysis
  3. a7 out of 8 rats
  4. b3 out of 7 animals showed CA without paresis I
  5. c5 out of 8 animals showed CA without paresis II