Fig. 5
From: Biologically consistent dose accumulation using daily patient imaging
Cumulative DVHs of case 3) and 9) (see Fig. 3), showing the planned dose, the conventional accumulated dose Da and the biological accumulated dose bEQDd for the three investigated fractionation schemes (standard α/β-values). For case 3) the distinct hot spot difference between bEQDd and Da is visible only as a small difference in the curves for the rectum in the DVH in the mid dose region, while no clear difference can be seen for CTV and bladder. Examples: Black arrow—dose regime where bEQDd increases the overdosage between planned and delivered dose further; blue arrow—the increase in the delivered dose calculation by bEQDd is still below the planned dose. For case 9) the strong difference hot spot in the rectum is also visible as a stronger difference in the DVH for hypofractionation with 5 fractions (fx)