Fig. 1
From: Biologically consistent dose accumulation using daily patient imaging
Schematic overview of the data acquisition, processing and analysis. Organ contours on the planning CT serve as basis for α/β-maps. Daily CTs are acquired in addition to the planning CT with an in-room CT scanner. On the basis of the initial dose plan and the daily CTs, daily delivered doses are forward calculated in the RayStation®. The RayStation®-integrated deformable image registration (DIR) is used to non-rigidly register the daily CTs to the planning CT. The derived deformation vector fields are then used to deform the forward calculated doses to compute the delivered dose in the anatomical frame of the planning CT (deformed delivered doses di). Using the individual di, the total dose is accumulated (Da) in the RayStation®. On the same basis of di, bEQDd is calculated (using the α/β-maps) according to Eq. 11. The two dose accumulation methods are compared in terms of the total dose difference (highlighted in green, top right)