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Table 10 Summary of the results from the fit of the two normal NTCP models for xerostomia and dry eye. AUC = area under the curve. Response rate is the average of the response rates predicted by the models. OR = Odds ratio. Threshold represent values of gEUD for the LKB model and \(\overline{\overline{D}}\) for the RS model

From: NTCP modeling and dose–volume correlations for acute xerostomia and dry eye after whole brain radiation

Parameters

AUC (95% CI)

OR (95% CI)

Threshold (95% CI)

LKB model

   

Xerostomia-Michigan

0.67 (0.49–0.83)

7.5 (2.9–16.6)

20 (18–22)

Xerostomia-Bother

0.69 (0.47–0.89)

7.7 (2.1–15.4)

20 (17–23)

Dry eye

0.56 (0.39–0.74)

3.9 (1.0–10.0)

29 (25–35)

RS model

   

Xerostomia-Michigan

0.67 (0.49–0.84)

7.1 (3.0–16.0)

20 (18–22)

Xerostomia-Bother

0.69 (0.46–0.89)

7.4 (1.9–15.4)

20 (17–22)

Dry eye

0.56 (0.39–0.73)

3.8 (1.0–10.0)

28 (25–35)