Skip to main content

Table 3 Dosimetric results for two kinds of VMAT plans. The corresponding statistical analyses were also included

From: Evaluation of a highly refined prediction model in knowledge-based volumetric modulated arc therapy planning for cervical cancer

  

CP

MP

p value

PGTVnd

V60Gy (%)

99.36 ± 0.59

99.40 ± 0.71

0.785

 

V66Gy (%)

0.15 ± 0.53

0.08 ± 0.35

0.095

 

Dmin(Gy)

59.12 ± 1.01

59.35 ± 0.73

0.131

 

CI

0.54 ± 0.11

0.54 ± 0.10

0.717

 

HI

0.05 ± 0.01

0.05 ± 0.01

0.444

PCTV

V45Gy (%)

99.48 ± 0.58

99.73 ± 0.20

0.011

 

V49.5 Gy (%)

16.04 ± 9.50

24.43 ± 12.16

 < 0.001

 

Dmin(Gy)

38.44 ± 10.87

39.49 ± 11.10

0.002

 

CI

0.81 ± 0.03

0.79 ± 0.03

0.001

 

HI

0.30 ± 0.06

0.30 ± 0.06

0.875

Spinal cord

D0.03 cc(Gy)

14.72 ± 13.67

15.42 ± 14.28

0.019

Bladder

Dmean(cGy)

3791.45 ± 704.91

4076.11 ± 743.14

 < 0.001

 

D35%(Gy)

43.79 ± 8.18

44.66 ± 7.95

0.004

 

V30(%)

75.92 ± 16.59

89.66 ± 18.34

 < 0.001

 

V40(%)

50.20 ± 15.19

66.03 ± 17.42

 < 0.001

 

V50(%)

3.67 ± 3.40

2.27 ± 2.72

0.003

Rectum

Dmean(cGy)

4189.89 ± 751.59

4301.27 ± 759.75

 < 0.001

 

D60%(Gy)

43.09 ± 7.82

44.31 ± 7.82

0.001

 

V30(%)

90.46 ± 16.36

93.09 ± 16.73

 < 0.001

 

V40(%)

75.40 ± 16.40

84.76 ± 16.64

 < 0.001

 

V50(%)

1.87 ± 3.79

1.24 ± 3.55

0.277

Kidney-L

Dmean(cGy)

427.02 ± 416.72

488.35 ± 486.71

0.001

 

V18(%)

3.22 ± 5.05

4.73 ± 7.19

0.019

Kidney-R

Dmean(cGy)

472.90 ± 390.95

575.53 ± 483.65

 < 0.001

 

V18(%)

2.65 ± 4.53

6.42 ± 7.10

 < 0.001

Femoral-L

Dmean (cGy)

1667.98 ± 438.95

2164.23 ± 541.71

 < 0.001

 

D0.03 cc(Gy)

41.23 ± 7.68

43.94 ± 7.76

 < 0.001

 

V30(%)

12.82 ± 6.76

26.61 ± 14.25

 < 0.001

 

V35(%)

5.91 ± 3.58

15.94 ± 8.77

 < 0.001

 

V40(%)

1.25 ± 1.54

6.24 ± 3.81

 < 0.001

 

V50(%)

/

/

/

Femoral-R

Dmean(cGy)

1551.25 ± 432.40

2117.46 ± 571.05

 < 0.001

 

D0.03cc(Gy)

39.70 ± 7.73

43.43 ± 7.84

 < 0.001

 

V30(%)

9.32 ± 8.71

24.51 ± 16.05

 < 0.001

 

V35(%)

4.01 ± 5.41

14.91 ± 13.59

 < 0.001

 

V40(%)

0.89 ± 2.04

6.25 ± 8.76

 < 0.001

 

V50(%)

/

/

/

  1. MP refers to the manual plan. CP refers to the clinically approved plan, which was created based on knowledge-based planning with possible manual adjustments thereafter. The CP was taken as our reference standard in this study