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Table 2 Dosimetric comparison of AP-1 vs. AP-6. The statistical results between AP-1 scores and AP-6 scores were also given

From: Evaluation of a highly refined prediction model in knowledge-based volumetric modulated arc therapy planning for cervical cancer

  

AP-1

AP-6

p value

Results

Scores

Results

Scores

PGTVnd

V60Gy (%)

94.19 ± 8.76

4.11 ± 2.77

96.86 ± 4.91

5.46 ± 2.73

 < 0.001

 

V66Gy (%)

0.00 ± 0.00

8.00 ± 0.00

0.00 ± 0.00

8.00 ± 0.00

/

 

Dmin (Gy)

58.16 ± 2.59

4.76 ± 0.92

58.52 ± 1.60

4.80 ± 0.77

0.159

 

CI

0.62 ± 0.11

1.24 ± 0.21

0.58 ± 0.11

1.16 ± 0.22

 < 0.001

 

HI

0.05 ± 0.02

1.90 ± 0.04

0.05 ± 0.02

1.89 ± 0.03

0.240

PCTV

V45Gy (%)

95.96 ± 6.94

4.79 ± 1.79

98.55 ± 3.16

6.81 ± 1.33

 < 0.001

 

V49.5 Gy (%)

13.67 ± 6.42

6.71 ± 1.92

18.90 ± 6.83

5.11 ± 2.05

 < 0.001

 

Dmin (Gy)

36.72 ± 10.69

2.23 ± 2.03

38.01 ± 10.79

3.05 ± 2.17

0.008

 

CI

0.84 ± 0.03

1.68 ± 0.06

0.82 ± 0.02

1.65 ± 0.04

 < 0.001

 

HI

0.32 ± 0.06

1.37 ± 0.12

0.30 ± 0.06

1.40 ± 0.11

0.095

Spinal cord

D0.03 cc (Gy)

14.13 ± 12.49

10.00 ± 0.00

14.38 ± 13.44

10.00 ± 0.00

/

Bladder

D35% (Gy)

42.84 ± 8.13

9.50 ± 0.61

43.54 ± 8.10

9.18 ± 0.88

 < 0.001

Rectum

D60.0%(Gy)

41.54 ± 7.47

7.72 ± 1.44

42.43 ± 7.63

7.40 ± 1.65

 < 0.001

Kidney (L)

V18Gy (%)

3.05 ± 4.71

5.00 ± 0.00

2.90 ± 4.60

5.00 ± 0.00

/

Kidney (R)

V18Gy (%)

3.16 ± 7.19

4.91 ± 0.53

2.32 ± 3.88

5.00 ± 0.00

0.324

Femoral head (L)

V35Gy (%)

7.80 ± 3.80

3.00 ± 0.02

5.59 ± 3.29

3.00 ± 0.00

0.211

D0.03 cc (Gy)

40.95 ± 7.47

2.00 ± 0.00

41.12 ± 7.61

2.00 ± 0.00

/

Femoral head (R)

V35Gy (%)

5.55 ± 4.79

2.96 ± 0.17

3.70 ± 4.96

2.96 ± 0.18

0.879

D0.03 cc (Gy)

38.98 ± 7.74

2.00 ± 0.00

39.48 ± 7.63

2.00 ± 0.00

/

Total score

  

83.92 ± 6.86

 

85.61 ± 6.78

0.013

  1. AP refers to the fully automatic plan, which was created by only one click at the “optimization” button with no other human intervention. AP-1 and AP-6 were fully automatic plans generated by using model C1 and model C6, respectively