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Table 2 Dosimetric comparison of AP-1 vs. AP-6. The statistical results between AP-1 scores and AP-6 scores were also given

From: Evaluation of a highly refined prediction model in knowledge-based volumetric modulated arc therapy planning for cervical cancer

   AP-1 AP-6 p value
Results Scores Results Scores
PGTVnd V60Gy (%) 94.19 ± 8.76 4.11 ± 2.77 96.86 ± 4.91 5.46 ± 2.73  < 0.001
  V66Gy (%) 0.00 ± 0.00 8.00 ± 0.00 0.00 ± 0.00 8.00 ± 0.00 /
  Dmin (Gy) 58.16 ± 2.59 4.76 ± 0.92 58.52 ± 1.60 4.80 ± 0.77 0.159
  CI 0.62 ± 0.11 1.24 ± 0.21 0.58 ± 0.11 1.16 ± 0.22  < 0.001
  HI 0.05 ± 0.02 1.90 ± 0.04 0.05 ± 0.02 1.89 ± 0.03 0.240
PCTV V45Gy (%) 95.96 ± 6.94 4.79 ± 1.79 98.55 ± 3.16 6.81 ± 1.33  < 0.001
  V49.5 Gy (%) 13.67 ± 6.42 6.71 ± 1.92 18.90 ± 6.83 5.11 ± 2.05  < 0.001
  Dmin (Gy) 36.72 ± 10.69 2.23 ± 2.03 38.01 ± 10.79 3.05 ± 2.17 0.008
  CI 0.84 ± 0.03 1.68 ± 0.06 0.82 ± 0.02 1.65 ± 0.04  < 0.001
  HI 0.32 ± 0.06 1.37 ± 0.12 0.30 ± 0.06 1.40 ± 0.11 0.095
Spinal cord D0.03 cc (Gy) 14.13 ± 12.49 10.00 ± 0.00 14.38 ± 13.44 10.00 ± 0.00 /
Bladder D35% (Gy) 42.84 ± 8.13 9.50 ± 0.61 43.54 ± 8.10 9.18 ± 0.88  < 0.001
Rectum D60.0%(Gy) 41.54 ± 7.47 7.72 ± 1.44 42.43 ± 7.63 7.40 ± 1.65  < 0.001
Kidney (L) V18Gy (%) 3.05 ± 4.71 5.00 ± 0.00 2.90 ± 4.60 5.00 ± 0.00 /
Kidney (R) V18Gy (%) 3.16 ± 7.19 4.91 ± 0.53 2.32 ± 3.88 5.00 ± 0.00 0.324
Femoral head (L) V35Gy (%) 7.80 ± 3.80 3.00 ± 0.02 5.59 ± 3.29 3.00 ± 0.00 0.211
D0.03 cc (Gy) 40.95 ± 7.47 2.00 ± 0.00 41.12 ± 7.61 2.00 ± 0.00 /
Femoral head (R) V35Gy (%) 5.55 ± 4.79 2.96 ± 0.17 3.70 ± 4.96 2.96 ± 0.18 0.879
D0.03 cc (Gy) 38.98 ± 7.74 2.00 ± 0.00 39.48 ± 7.63 2.00 ± 0.00 /
Total score    83.92 ± 6.86   85.61 ± 6.78 0.013
  1. AP refers to the fully automatic plan, which was created by only one click at the “optimization” button with no other human intervention. AP-1 and AP-6 were fully automatic plans generated by using model C1 and model C6, respectively
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Radiation Oncology

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