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Table 1 Risk factors for lymph node metastases

From: Topographic distribution of lymph node metastasis in patients with stage IB1 cervical cancer: an analysis of 8314 lymph nodes

Risk factors

Variable

Patients

Node positive (%)

P2 test)

Age (years)

 < 50

187

32 (17.11)

0.227

 ≥ 50

102

12 (11.76)

 

BMI (kg/m2)

 ≥ 25

52

1 (1.92)

0.025

 < 25

225

37 (16.44)

 

Unknown

12

  

Menopausal

Premenopause

192

31 (16.15)

0.610

Postmenopause

94

13 (13.83)

 

Tumor size

 < 2 cm

87

3 (3.45)

 < 0.001

 ≥ 2 cm

197

40 (20.30)

 

Pathologic type

Squamous cell cancer

216

36 (16.67)

0.241

Others

73

8 (10.96)

 

Histologic grading

 < G2

31

2 (6.45)

0.229

 ≥ G2

254

42 (16.54)

 

 < G3

202

28 (13.86)

0.250

 ≥ G3

83

16 (19.28)

 

Parametrium invasion

Absent

265

32 (12.08)

 < 0.001

Present

24 (8.3%)

12 (50.00)

 

Stromal invasion

Inner one-third

126

11 (8.73)

0.012

Middle one-third

72

14 (19.44)

 

Outer one-third

82

19 (23.17)

 

Stromal invasion

Inner two-third

209

25 (11.96)

0.018

Outer one-third

82

19 (23.17)

 

Lymphovascular space involvement (LVSI)

Absent

192

17 (8.85)

 < 0.001

Present

97 (33.6)

27 (27.84)

 

Removed lymph nodes

 < 30

144

24 (16.67)

0.497

 ≥ 30

145

20 (13.79)