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Table 4 Univariate and multivariate analyses of RRP in 73 patients with LS-SCLC treated with early CCRT

From: Chemoradiotherapy for limited-stage small-cell lung cancer and interstitial lung abnormalities

Variable Univariate analysis Multivariate analysis
HR 95% CI P value HR 95% CI P value
Sex male 4.74 0.83–89.7 0.0850 5.29 0.68–123 0.1221
Age ≥ 70 years 1.33 0.32–4.77 0.6717
ECOG-PS = 0 1.22 0.36–4.46 0.7464
V20 ≥ 25% 2.03 0.61–7.42 0.2526 3.64 0.82–20.9 0.0900
Pre-existing ILAs 16.3 3.88–80.3 0.0001 27.7 3.73–105 0.0002
  1. RRP, radiation-related pneumonitis; LS-SCLC, limited-stage small-cell lung cancer; CCRT, concurrent chemoradiotherapy; HR, hazard ratio; CI, confidence interval; ECOG-PS, Eastern Cooperative Oncology Group performance status; V20, percentage of normal lung receiving at least 20 Gy; ILA, interstitial lung abnormality;