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Table 4 Univariate and multivariate analyses of RRP in 73 patients with LS-SCLC treated with early CCRT

From: Chemoradiotherapy for limited-stage small-cell lung cancer and interstitial lung abnormalities

Variable

Univariate analysis

Multivariate analysis

HR

95% CI

P value

HR

95% CI

P value

Sex male

4.74

0.83–89.7

0.0850

5.29

0.68–123

0.1221

Age ≥ 70 years

1.33

0.32–4.77

0.6717

ECOG-PS = 0

1.22

0.36–4.46

0.7464

V20 ≥ 25%

2.03

0.61–7.42

0.2526

3.64

0.82–20.9

0.0900

Pre-existing ILAs

16.3

3.88–80.3

0.0001

27.7

3.73–105

0.0002

  1. RRP, radiation-related pneumonitis; LS-SCLC, limited-stage small-cell lung cancer; CCRT, concurrent chemoradiotherapy; HR, hazard ratio; CI, confidence interval; ECOG-PS, Eastern Cooperative Oncology Group performance status; V20, percentage of normal lung receiving at least 20 Gy; ILA, interstitial lung abnormality;