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Table 2 Recommendations for 3–5 fractions SBRT treatment

From: Optimal stereotactic body radiotherapy dosage for hepatocellular carcinoma: a multicenter study

Dosimetric constraints for normal liver Radiation dose for GTV
V15 < 21.5%, VS10 ≥ 621.8 mL SaRT: BED10 ≥ 100 Gy
V15 < 33.1%, VS10 ≥ 416.2–621.8 mL SbRT: EQD2 ≥ 74 Gy
Without above conditions or Child–Pugh ≥ B7 class ScRT: EQD2 < 74 Gy
  1. GTV, gross tumor volume; V15, percentage of normal liver volume receiving more than 15 Gy; VS10, absolute normal liver volume spared from at least 10 Gy