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Table 1 Combining losartan with radiotherapy in HER2/neu-positive metastatic MCa-M3C tumors

From: Combining losartan with radiotherapy increases tumor control and inhibits lung metastases from a HER2/neu-positive orthotopic breast cancer model

Group (N = mice)

Lung macro metastases

 >  = 3 nodules

 < 3 nodules;

0 nodule

Chi-square (χ2) test

Control N = 8

5

2

1

 

Losartan N = 8

3

3

2

Los vs Control P > 0.05

20 Gy IR N = 8

2

2

4

IR w Control P > 0.05

Los + IR N = 8

0

3

5

Los + IR vs control P < 0.025