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Fig. 4 | Radiation Oncology

Fig. 4

From: Combining losartan with radiotherapy increases tumor control and inhibits lung metastases from a HER2/neu-positive orthotopic breast cancer model

Fig. 4

Combining losartan with radiotherapy increased MCa-M3C tumor host survival; and losartan treatment increased tumor vessel fraction. a Kaplan–Meier survival curve shows that combining losartan with 20 Gy IR (Los + IR) significantly increased host survival (Los + IR vs. Control P = 0.0303). b Tumor vessels imaging measurement of MCa-M3C tumors growth in MFP windows by MPLSM at day 0 and day 3 post-treatment. Result showed losartan treatment significantly increased tumor vessel fraction (Area of blood vessels/field area, Unpaired t test, P = 0.0314)

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