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Fig. 2 | Radiation Oncology

Fig. 2

From: Combining losartan with radiotherapy increases tumor control and inhibits lung metastases from a HER2/neu-positive orthotopic breast cancer model

Fig. 2

MCa-M3C tumor histological features and lung metastases. a Spontaneous lung metastases from MCa-M3C tumor implanted in FVB/N mouse MFP. b Photomicrograph of the section of MCa-M3C MFP tumor isograft showing adenocarcinoma histological features, with a glandular-epithelial growth patterns (*); abundant tumor stroma (S); and tumor cell mitotic figures (arrows). H&E stain; Bar = 100 µm. c Photomicrograph of a section of MCa-M3C metastasis in lung (M), showing tumor cells and the growth pattern similar to that in the primary MFP tumor. H&E stain; Bar = 100 µm. d  Masson’s Trichrome staining of MCa-M3C MFP tumor isograft reveals a high collagen density (S, positive light blue stain) Bar = 100 µm

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Radiation Oncology

ISSN: 1748-717X

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