Clinical outcomes of extensive-stage small cell lung cancer patients treated with thoracic radiotherapy at different times and fractionations

Table 2 Clinical characteristics of ES-SCLC patients based on the radiation dose

Variables		Low -dose	High-dose	p value
Age, y	< 60	77	40
	≥ 60	82	45	0.838
Sex	Male	128	64
	Female	31	21	0.344
ECOG PS score	0–1	149	77
	2	10	8	0.374
Smoking index	≥ 400	79	41
	< 400	80	44	0.829
Metastatic organs	Single	56	38
	Multiple	103	47	0.147
Number of metastases	≤ 2	31	18
	> 2	128	67	0.755
Brain metastasis	Yes	97	51
	No	62	34	0.878
Liver metastasis	Yes	50	22
	No	109	63	0.364
Bone metastasis	Yes	68	30
	No	91	55	0.257
Weight loss	Yes	24	7
	No	135	78	0.125
PCI	Yes	12	4
	No	147	81	0.588

ES-SCLC, Extensive-stage small-cell lung cancer; ECOG PS, Eastern Cooperative Oncology Group performance status; PCI, Prophylactic cranial irradiation;

ISSN: 1748-717X