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Table 2 Univariate logistic regression analysis of the risk factors of grade ≥ 2 radiation pneumonitis

From: Overlap time is an independent risk factor of radiation pneumonitis for patients treated with simultaneous EGFR-TKI and thoracic radiotherapy

Factor

P value

OR (95% CI)

Total lung V5

0.188

1.02 (0.99–1.06)

Total lung V10

0.069

1.02 (1.00–1.09)

Total lung V15

0.040

1.06 (1.00–1.13)

Total lung V20

0.036

1.08 (1.01–1.16)

Total lung V30

0.032

1.11 (1.01–1.22)

Total lung MLD

0.117

1.11 (0.98–1.25)

Ipsilateral lung V5

0.090

1.02 (1.00–1.05)

Ipsilateral lung V10

0.054

1.03 (1.00–1.06)

Ipsilateral lung V15

0.021

1.04 (1.01–1.08)

Ipsilateral lung V20

0.011

1.06 (1.01–1.10)

Ipsilateral lung V30

0.009

1.07 (1.02–1.13)

Ipsilateral lung MLD

0.035

1.09 (1.01–1.17)

  1. The bold text was some risk factor of RP, which were significantly correlated with RP and the p-value < 0.05
  2. MLD mean lung dose, RP radiation pneumonitis