Table 4 Univariate analyses of distant intracranial control (DIC) and overall survival (OS) of the 28 patients
| Variable | Patients (n=) | 1 yr-DIC (%) | p-value | 1 yr-OS (%) | p-value |
|---|---|---|---|---|---|
| Gender | |||||
| Male | 17 | 49.2 | 61.2 | ||
| Female | 11 | 60.6 | 0.216 | 72.7 | 0.426 |
| BRAF status | |||||
| BRAF V600-E-Mutation | 14 | 40.1 | 63.5 | ||
| No BRAF V600-E-Mutation | 14 | 54.4 | 0.297 | 69.6 | 0.382 |
| Melanoma-molGPA | |||||
| 0.5–1.0 | 2 | 50.0 | 0 | ||
| 1.5–2.0 | 11 | 32.7 | 14.5 | ||
| 2.5–3.0 | 11 | 49.7 | 53.0 | ||
| 3.5–4.0 | 4 | 50.0 | 0.535 | 75.0 | 0.087 |
| Number of brain metastases | |||||
| 1 | 12 | 47.6 | 72.7 | ||
| 2 | 7 | 53.6 | 57.1 | ||
| 3 | 6 | 62.5 | 50.0 | ||
| > 3 | 3 | 0 | 0.011 | 0 | 0.629 |
| Targeted/ immunotherapy | |||||
| Concurrent | 19 | 47.7 | 64.8 | ||
| No/ sequential | 9 | 50.0 | 0.933 | 55.6 | 0.233 |