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Table 4 Univariate analyses of distant intracranial control (DIC) and overall survival (OS) of the 28 patients

From: Stereotactic radiosurgery combined with targeted/ immunotherapy in patients with melanoma brain metastasis

VariablePatients (n=)1 yr-DIC (%)p-value1 yr-OS (%)p-value
Gender
 Male1749.2 61.2 
 Female1160.60.21672.70.426
BRAF status
 BRAF V600-E-Mutation1440.1 63.5 
 No BRAF V600-E-Mutation1454.40.29769.60.382
Melanoma-molGPA
 0.5–1.0250.0 0 
 1.5–2.01132.7 14.5 
 2.5–3.01149.7 53.0 
 3.5–4.0450.00.53575.00.087
Number of brain metastases
 11247.6 72.7 
 2753.6 57.1 
 3662.5 50.0 
  > 3300.01100.629
Targeted/ immunotherapy
 Concurrent1947.7 64.8 
 No/ sequential950.00.93355.60.233