Location of metastasis |
Left | 26 | 50.0% |
Right | 25 | 48.1% |
Midline | 1 | 1.9% |
Frontal | 19 | 36.5% |
Parietal | 6 | 11.5% |
Temporal | 8 | 15.4% |
Occipital | 6 | 11.5% |
Frontotemporal | 1 | 1.9% |
Temporoparietal | 1 | 1.9% |
Parietooccipital | 1 | 1.9% |
Cerebellum | 3 | 5.8% |
Others (basal ganglia, insular cortex, parahippocampal, parafalcin) | 7 | 13.5% |
GTV to PTV margin (mm) |
2 mm | 24 | 46.2% |
3 mm | 28 | 53.8% |
Prescribed dose (Gy) |
15 | 1 | 1.9% |
17 | 2 | 3.8% |
18 | 17 | 32.7% |
20 | 30 | 57.7% |
24 | 2 | 3.8% |
Prescribed isodose (%) |
70 | 1 | 1.9% |
80 | 51 | 98.1% |
Treatment planning software |
Oncentra Masterplan | 30 | 57.7% |
Monaco | 17 | 32.7% |
Radionics | 5 | 9.6% |
Fixation technique |
Frameless Brainlab mask | 9 | 17.3% |
Frameless double thermoplastic mask | 38 | 73.1% |
Invasive fixed head frame | 5 | 9.6% |
Targeted/ immunotherapy (TT/IT) |
BRAFi | 5 | 9.6% |
MEKi | 1 | 1.9% |
Anti-CTLA-4 | 4 | 7.7% |
Anti-PD1 | 14 | 26.9% |
BRAFi+MEKi | 6 | 11.5% |
Anti-PD1 + Anti-CTLA-4 | 10 | 19.2% |
Triple combination | 2 | 3.8% |
none | 10 | 19.2% |
Application of TT/IT |
Before SRS (median: 9.5 days, range: 3-43 days) | 24 | 46.2% |
Concurrent before SRS (median: 8 days, range: 3–21 days) | 21 | 40.4% |
After SRS (median: 9 days, range: 2–97 days) | 39 | 75.0% |
Concurrent after SRS (median: 8 days, range: 2–27 days) | 15 | 28.8% |
Concurrent (4 weeks before or 4 weeks after SRS) | 36 | 69.2% |