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Table 3 Univariate and multivariate analysis of clinical parameters regarding OS in elderly HNSCC patients receiving radiotherapy or chemoradiotherapy

From: Radiotherapy for geriatric head-and-neck cancer patients: what is the value of standard treatment in the elderly?

Parameter

HR

CI 95%

p-value

Univariate

 Age ≥ 75 / 65–74 years

1.584

1.101–2.280

0.013

 Smoker / non-smoker

1.731

1.045–2.868

0.033

 GFR < 60 / ≥ 60 ml/min/1.73m2

1.537

1.024–2.308

0.038

 Chemotherapy non-completed / completed

1.481

1.025–2.140

0.037

 Karnofsky < 80 / ≥ 80%

2.803

1.817–4.324

< 0.001

Multivariate

 Age ≥ 75 / 65–74 years

1.564

0.962–2.543

0.072

 Smoker / non-smoker

1.960

1.109–3.464

0.020

 GFR < 60 / ≥ 60 ml/min/1.73m2

1.047

0.612–1.791

0.868

 Chemotherapy non-completed / completed

0.852

0.736–1.174

0.501

 Karnofsky < 80 / ≥ 80%

2.584

1.561–4.274

< 0.001