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Table 3 Univariate and multivariate analysis of clinical parameters regarding OS in elderly HNSCC patients receiving radiotherapy or chemoradiotherapy

From: Radiotherapy for geriatric head-and-neck cancer patients: what is the value of standard treatment in the elderly?

Parameter HR CI 95% p-value
Univariate
 Age ≥ 75 / 65–74 years 1.584 1.101–2.280 0.013
 Smoker / non-smoker 1.731 1.045–2.868 0.033
 GFR < 60 / ≥ 60 ml/min/1.73m2 1.537 1.024–2.308 0.038
 Chemotherapy non-completed / completed 1.481 1.025–2.140 0.037
 Karnofsky < 80 / ≥ 80% 2.803 1.817–4.324 < 0.001
Multivariate
 Age ≥ 75 / 65–74 years 1.564 0.962–2.543 0.072
 Smoker / non-smoker 1.960 1.109–3.464 0.020
 GFR < 60 / ≥ 60 ml/min/1.73m2 1.047 0.612–1.791 0.868
 Chemotherapy non-completed / completed 0.852 0.736–1.174 0.501
 Karnofsky < 80 / ≥ 80% 2.584 1.561–4.274 < 0.001