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Table 4 Predicted Probability of Symptomatic Radiation Pneumonitis

From: Correlation of dosimetric factors with the development of symptomatic radiation pneumonitis in stereotactic body radiotherapy

Metric

Predicted Probability

C-statistic

20%

33%

50%

V5

28.5%

33.0%

37.6%

0.918

V10

17.5%

20.2%

23.0%

0.918

V15

11.6%

13.6%

15.7%

0.935

V20

8.1%

9.7%

11.5%

0.928

V25

6.0%

7.4%

8.8%

0.916

V30

4.7%

5.8%

7.0%

0.904

V40

3.1%

3.9%

4.8%

0.885

V12.4

451.0 cc

538.2 cc

629.2 cc

0.893

V13.5

407.7 cc

491.5 cc

579.1 cc

0.890

Total MLD

5.5 Gy

6.3 Gy

7.1 Gy

0.925

Contralateral MLD

2.4 Gy

2.8 Gy

3.3 Gy

0.929

Ipsilateral MLD

8.3 Gy

9.0 Gy

9.6 Gy

0.952

Contralateral V5

19.3%

25.7%

32.1%

0.821

Ipsilateral V30

8.2%

9.3%

10.4%

0.937

Ipsilateral V40

5.2%

6.1%

6.9%

0.919

  1. Abbreviations: Vdose is the percent of lung receiving greater than the “dose” (in Gy). MLD = Mean Lung Dose. Symptomatic Radiation Pneumonitis = RTOG G3+ or CTCAE G2+ RP. For example, a 33% predicted probability of developing symptomatic RP is associated with a V20 of 9.7% or a MLD of 6.3 Gy, respectively
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Radiation Oncology

ISSN: 1748-717X

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