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Table 2 Summary of the dose volume histogram analysis for the organs at risk for the node positive patients

From: Treatment planning comparison of volumetric modulated arc therapy employing a dual-layer stacked multi-leaf collimator and helical tomotherapy for cervix uteri

Parameter

Objective

Halcyon (H)

Helical Tomotherapy (HT)

Difference (H-HT)

p

Bowel

 Mean [Gy]

Minimise

21.2 ± 3.1

21.1 ± 2.8

0.1 ± 0.9

0.82

 D1% [Gy]

≤57.5

48.8 ± 1.7

47.4 ± 1.3

1.4 ± 0.7

< 0.001

 V40Gy [cm3]

≤250 a

226.3 ± 35.9

258.9 ± 60.5

−32.6 ± 34.3

0.01

 V30Gy [cm3]

≤500 a

413.4 ± 58.9

472.7 ± 90.0

−59.4 ± 53.5

0.01

 V15Gy [cm3]

≤700 b

1557.2 ± 359.9

1279.7 ± 296.5

277.4 ± 188.6

0.01

Sigmoid

 D1% [Gy]

≤57.5

50.5 ± 3.7

49.4 ± 3.8

1.1 ± 2.1

0.11

Bladder

 D1% [Gy]

≤57.5

48.8 ± 2.2

47.0 ± 1.1

1.8 ± 1.8

0.01

 V40Gy [%]

≤75 a

60.0 ± 10.8

63.6 ± 16.6

−3.6 ± 7.5

0.16

 V30Gy [%]

≤85 a

76.9 ± 7.1

77.0 ± 12.5

−0.1 ± 9.2

0.96

Rectum

 D1% [Gy]

≤57.5

48.1 ± 1.3

46.9 ± 0.7

1.2 ± 1.8

0.05

 V40Gy [%]

≤85 a

66.6 ± 20.5

72.8 ± 21.7

−6.2 ± 11.2

0.11

 V30Gy [%]

≤95 a

81.9 ± 12.7

89.7 ± 14.7

−7.8 ± 12.2

0.07

Spinal Cord

 D1% [Gy]

≤48.0

25.1 ± 17.9

25.6 ± 16.5

−2.4 ± 4.4

0.12

Left Fem. Head

 D1% [Gy]

≤50.0

38.1 ± 3.6

39.4 ± 1.6

−1.3 ± 3.2

0.24

 Mean [Gy]

b

16.4 ± 2.7

13.8 ± 2.5

2.6 ± 3.1

0.001

Right Fem. Head

 D1% [Gy]

≤50.0

36.3 ± 4.6

41.7 ± 2.9

−5.4 ± 2.5

< 0.001

 Mean [Gy]

b

16.1 ± 2.3

12.6 ± 1.3

3.5 ± 1.9

< 0.001

Left Kidney

 Mean [Gy]

≤15

6.9 ± 5.0

7.5 ± 5.1

−0.6 ± 1.5

0.22

Right Kidney

 Mean [Gy]

≤

6.6 ± 4.8

7.1 ± 4.2

− 0.5 ± 2.1

0.52

Body

 D1% [Gy]

≤58.9

53.2 ± 1.4

49.9 ± 3.7

3.3 ± 4.1

< 0.001

 CI36Gy

< 1.6 b

1.6 ± 0.2

2.0 ± 0.1

−0.4 ± 0.2

< 0.001

 CI43Gy

< 1.1 b

1.1 ± 0.1

1.3 ± 0.1

−0.2 ± 0.1

< 0.001

 CIPaddick

b

0.87 ± 0.04

0.90 ± 0.07

−0.03 ± 0.08

0.01

 CIPaddick_SIB

b

0.71 ± 0.08

0.78 ± 0.15

−0.07 ± 0.10

0.05

  1. Vx%: volume receiving at least x% of the dose. Dx%: dose received by at least x% of the volume
  2. a: soft constraints, expected to be fulfilled in 70–80% of the patients according to EMBRACE II guidelines
  3. b: not included as optimisation constraint