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Table 1 Univariate Cox proportional hazard model of overall survival and margins between contrast enriching tumor volumes and beam collimation settings

From: Contrast-enhanced, conebeam CT-based, fractionated radiotherapy and follow-up monitoring of orthotopic mouse glioblastoma: a proof-of-concept study

Variable (Univariate analyses)

Hazard ratio (95% Confidence interval)

P-value

P-value adjusted (Bonferroni-Holm)

Margin H-axis mean over time (d7, d10, d14, d17) [mm]

0.53 (0.35–0.81)

0.0034

0.0136

Margin H-axis d7 [mm]

0.67 (0.50–0.90)

0.0088

0.0264

Margin L-axis mean over time (d7, d10, d14, d17) [mm]

0.50 (0.26–0.93)

0.0284

0.0568

Margin L-axis d7 [mm]

0.65 (0.32–1.32)

0.2318

0.2318

  1. Margin sizes between contrast enriching tumor volumes and beam collimation settings in H- and L-axis [mm] as means over time (d7, d10, d14, d17) or as single values of d7 and overall survival times [d] were subjected to univariate Cox proportional hazard model analyses and post-hoc Bonferroni-Holm correction