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Table 1 The mean, minimal and maximal value of the parameters for evaluation of PTV coverage and OARs constraints of all plans. Data analysis for comparison between manual plans and autoplans was done with paired two-tailed t-test. A p-value less than 0.05 was considered statistically significant

From: Automated Hypofractionated IMRT treatment planning for early-stage breast Cancer

 

Manual

Auto

 

Parameter

Mean value ± SD [Min, Max]

Mean value ± SD [Min, Max]

p-value

Body

 V110%[%]

0.07 ± 0.29 [0.0, 2.15]

0.03 ± 0.23 [0.0, 2.15]

0.29

PTV

 V95%[%]

98.5 ± 0.5 [96.7, 99.5]

98.5 ± 0.6 [96.4, 99.9]

0.40

Ipsilateral lung

 V16Gy[%]

14.0 ± 3.6 [5.1, 28.3]

13.3 ± 3.0 [4.3, 26.9]

< 0.01

 Mean[Gy]

6.6 ± 1.5 [3.0, 12.7]

6.3 ± 1.2 [2.7, 10.9]

< 0.01

Heart

 V20Gy[%]

0.90 ± 1.30 [0.0, 8.0]

0.90 ± 1.10 [0.0, 4.4]

0.79

 Mean[Gy]

1.4 ± 0.6 [0.5, 4.0]

1.4 ± 0.6 [0.6, 3.3]

0.30

Contralateral breast

 V5Gy[%]

0.22 ± 1.29 [0.0, 10.40]

0.46 ± 2.50 [0.0, 22.83]

0.31

 Max[Gy]

3.5 ± 7.3 [0.2, 43.8]

5.0 ± 8.7 [0.2, 44.6]

< 0.01

CI

1.30 ± 0.09 [1.10, 1.63]

1.24 ± 0.06 [1.14, 1.41]

< 0.01

HI

1.08 ± 0.02 [1.05, 1.13]

1.07 ± 0.02 [1.05, 1.13]

< 0.01

MU

1205 ± 187 [775, 1650]

1010 ± 46 [772, 1353]

< 0.01