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Table 1 The mean, minimal and maximal value of the parameters for evaluation of PTV coverage and OARs constraints of all plans. Data analysis for comparison between manual plans and autoplans was done with paired two-tailed t-test. A p-value less than 0.05 was considered statistically significant

From: Automated Hypofractionated IMRT treatment planning for early-stage breast Cancer

 ManualAuto 
ParameterMean value ± SD [Min, Max]Mean value ± SD [Min, Max]p-value
Body
 V110%[%]0.07 ± 0.29 [0.0, 2.15]0.03 ± 0.23 [0.0, 2.15]0.29
PTV
 V95%[%]98.5 ± 0.5 [96.7, 99.5]98.5 ± 0.6 [96.4, 99.9]0.40
Ipsilateral lung
 V16Gy[%]14.0 ± 3.6 [5.1, 28.3]13.3 ± 3.0 [4.3, 26.9]< 0.01
 Mean[Gy]6.6 ± 1.5 [3.0, 12.7]6.3 ± 1.2 [2.7, 10.9]< 0.01
Heart
 V20Gy[%]0.90 ± 1.30 [0.0, 8.0]0.90 ± 1.10 [0.0, 4.4]0.79
 Mean[Gy]1.4 ± 0.6 [0.5, 4.0]1.4 ± 0.6 [0.6, 3.3]0.30
Contralateral breast
 V5Gy[%]0.22 ± 1.29 [0.0, 10.40]0.46 ± 2.50 [0.0, 22.83]0.31
 Max[Gy]3.5 ± 7.3 [0.2, 43.8]5.0 ± 8.7 [0.2, 44.6]< 0.01
CI1.30 ± 0.09 [1.10, 1.63]1.24 ± 0.06 [1.14, 1.41]< 0.01
HI1.08 ± 0.02 [1.05, 1.13]1.07 ± 0.02 [1.05, 1.13]< 0.01
MU1205 ± 187 [775, 1650]1010 ± 46 [772, 1353]< 0.01