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Table 3 Univariate analysis and multivariate model of factors associated with overall survival in patients receiving curative intent therapy. HR > 1.0 indicates increased risk of death

From: Population-based analysis of curative therapies in stage II non-small cell lung cancer: the role of radiotherapy in medically inoperable patients

 UVAMVA
HRp-valueHR95% CIp-value
GroupSurgeryRef< 0.001Ref  
 Radiation2.062 1.7301.284–2.330< 0.001
Age 1.038< 0.0011.0130.998–1.0290.094
SexFemaleRef0.354Ref  
 Male1.094 0.9790.757–1.2670.873
HistologyAdenocarcinomaRef Ref  
 Squamous1.571< 0.0011.0410.761–1.4230.802
 NOS/other1.997< 0.0010.9550.679–1.3420.791
ECOG0–1Ref< 0.001Ref  
 > = 22.156 1.5901.210–2.0900.001
Weight loss< 5%Ref Ref  
 5–10%1.1000.5100.8470.585–1.2260.378
 > 10%2.294< 0.0011.6681.139–2.4440.009
 unk1.1050.4380.7830.539–1.1360.197
SmokingNeverRef Ref  
 Former1.3910.1261.0970.595–2.0200.767
 Current1.3980.1241.2530.667–2.3540.484
ChemotherapyNoRef< 0.001Ref  
 Yes0.560 0.7070.524–0.9540.023
  1. UVA univariate analysis, MVA multivariate analysis, HR hazard ratio, CI confidence interval, Ref reference group