From: Optimal radiotherapy for patients with internal mammary lymph node metastasis from breast cancer
Characteristics | Number of patients (%) | p-value | ||
---|---|---|---|---|
≤ 40 years (n = 38) | > 40 years(n = 46) | |||
Follow-up duration | Median months (range) | 58.5 mo (15–111) | 59.0 mo (12–104) | 0.215 1) |
Histologic grade | 1–2 | 22 (57.9%) | 23 (50.0%) | 0.163 |
3 | 10 (26.3%) | 20 (43.5%) | ||
Subtypes | Non-TNBC | 25 (65.8%) | 29 (63.0%) | 0.974 |
TNBC | 13 (34.2%) | 17 (37.0%) | ||
cT stages | 1–2 | 27 (71.1%) | 28 (60.9%) | 0.916 |
3–4 | 11 (28.9%) | 18 (39.1%) | ||
cN stages | 2b or 3b | 27 (71.1%) | 36 (78.3%) | 0.613 |
3c | 11 (28.9%) | 10 (21.7%) | ||
FNABx for IMN | (−) or unknown | 16 (42.1%) | 28 (60.9%) | 0.135 |
(+) | 22 (57.9%) | 18 (39.1%) | ||
Extent of the IMN | Single ICS | 18 (47.4%) | 19 (41.3%) | 0.737 |
Multiple ICS | 20 (52.6%) | 27 (58.7%) | ||
IMN long diameter | < 1.0 cm | 20 (52.6%) | 22 (47.8%) | 0.826 |
≥ 1.0 cm | 18 (47.4%) | 24 (52.2%) | ||
Neoadjuvant chemotherapy | Not done | 7 (18.4%) | 11 (23.9%) | 0.731 |
Done | 31 (81.6%) | 35 (76.1%) | ||
Primary surgery | BCS | 20 (52.6%) | 20 (43.5%) | 0.538 |
Mastectomy | 18 (47.4%) | 26 (56.5%) | ||
Axillary surgery | ALND | 32 (84.2%) | 42 (91.3%) | 0.509 |
SLNB | 6 (15.8%) | 4 (8.7%) | ||
RT dose to IMN 2) | 50–63.5 Gy | 15 (39.5%) | 20 (43.5%) | 0.882 |
63.6–70.4 Gy | 23 (60.5%) | 26 (56.5%) |