From: Optimal radiotherapy for patients with internal mammary lymph node metastasis from breast cancer
Characteristics | Number of patients (%) | |
---|---|---|
Age (years) | ≤40 | 38 (45.2%) |
> 40 | 46 (54.8%) | |
Laterality of breast cancer | Left breast | 57 (67.9%) |
Right breast | 27 (32.1%) | |
Location of breast cancer | Inner or center part | 66 (78.6%) |
Outer part | 18 (21.4%) | |
Histologic type | Invasive ductal carcinoma | 78 (92.9%) |
Others | 6 (7.1%) | |
Histologic grade | 1–2 | 45 (53.6%) |
3 | 30 (35.7%) | |
Unknown | 9 (10.7%) | |
Tumor subtype | ER+/or PR+/HER2- | 32 (38.1%) |
ER+/or PR+/HER2+ | 12 (14.3%) | |
ER−/PR−/HER2+ | 10 (11.9%) | |
ER−/PR−/HER2- | 30 (35.7%) | |
cT stage | T1-T2 | 47 (56.0%) |
T3-T4 | 37 (44.0%) | |
cN stage | N2b or N3b | 63 (75.0%) |
N3c | 21 (25.0%) | |
Extent of IMN | Single ICS | 37 (44.0%) |
Multiple ICS | 47 (56.0%) | |
Long diameter of the IMN | < 1.0 cm | 42 (50.0%) |
≥1.0 cm | 42 (50.0%) | |
Type of breast surgery | Breast-conserving surgery | 40 (47.6%) |
Mastectomy | 44 (52.4%) | |
Type of axillary surgery | Sentinel lymph node biopsy | 10 (11.9%) |
Axillary lymph node dissection | 74 (88.1%) | |
Neoadjuvant chemotherapy | Performed | 66 (78.6%) |
Not performed | 18 (21.4%) | |
EQD2 of the IMN1) | 50.0–63.5 Gy | 35 (41.7%) |
(median, 63.6 Gy; range, 50–70.4 Gy) | 63.6–70.4 Gy | 49 (58.3%) |