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Table 2 Dose to the organs at risk for all patients and all fractions

From: Dosimetric benefit of an adaptive treatment by means of plan selection for rectal cancer patients in both short and long course radiation therapy

 

Dose per fraction

Median values (range)

p-value

ART

Non-ART

LCRT (25 × 2 Gy)

 Bladder

V15Gy

(%)

99.8 (87.6–100.0)

100.0 (85.6–100.0)

<  0.001

V30Gy

(%)

43.0 (12.6–99.3)

49.6 (19.1–96.8)

<  0.001

V40Gy

(%)

22.8 (1.8–91.1)

29.0 (4.2–85.3)

<  0.001

V45Gy

(%)

15.0 (0.2–87.0)

21.8 (0.4–77.6)

<  0.001

V95%

(%)

10.8 (0.0–82.2)

17.8 (0.0–72.4)

<  0.001

Dmean

(Gy)

1.2 (0.9–2.0)

1.3 (1.0–1.9)

<  0.001

 Small Bowel

V15Gy

(cm3)

847 (332–1447)

853 (294–1363)

0.001

V30Gy

(cm3)

309 (119–554)

309 (120–557)

0.542

V40Gy

(cm3)

205 (99–431)

214 (99–434)

<  0.001

V45Gy

(cm3)

179 (93–381)

187 (90–390)

<  0.001

V95%

(cm3)

160 (83–358)

170 (82–366)

<  0.001

SCRT (5 × 5 Gy)

 Bladder

V15Gy

(%)

29.7 (5.7–58.6)

33.8 (9.9–60.5)

0.001

V95%

(%)

4.4 (0.0–16.4)

7.1 (0.0–27.7)

0.013

Dmean

(Gy)

2.7 (2.1–3.5)

2.8 (2.3–3.6)

0.001

 Small Bowel

V15Gy

(cm3)

329 (139–456)

317 (137–477)

0.237

V95%

(cm3)

176 (87–274)

191 (93–275)

0.135

  1. Total dose V15Gy, V30Gy, V40Gy, V45Gy for LCRT corresponding to fraction dose V0.6Gy, V1.2Gy, V1.6Gy, V1.8Gy respectively and V15Gy total dose for SCRT corresponding to V3.0Gy fraction dose