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Table 3 Characteristic parameters with tumor response

From: Clinical predictors of pathological good response in locally advanced rectal cancer

Variables

Classification

Tumor response

p

ypT0–1N0

ypT2–4N0/ypTanyN + 

Gender

   

0.523

Male

32

71

 

Female

25

45

 

Age (years)

   

0.237

 < 60

29

70

 

 ≥ 60

28

46

 

The distance from anal verge (cm)

   

0.007

 < 5

33

42

 

 ≥ 5

24

74

 

cT classification

   

 < 0.001

2

9

1

 

3

16

53

 

4

32

62

 

cN classification

   

0.513

0

3

4

 

1

17

27

 

2

37

85

 

Clinical stage

   

0.874

II

3

4

 

III

54

112

 

Pretreatment CEA (ng/mL)

   

0.006

 < 5

41

58

 

 ≥ 5

16

58

 

Posttreatment CA199 (U/mL)

   

0.799

 < 37

52

106

 

 ≥ 37

5

10

 

Pretreatment CEA (ng/mL)

   

0.690

 < 5

49

97

 

 ≥ 5

8

19

 

Posttreatment CA199 (U/mL)

   

0.735

 < 37

54

110

 

 ≥ 37

3

6

 

Concurrent chemotherapy

   

0.127

Capecitabine

21

57

 

Capox

36

59

 

CRM

   

0.594

Positive

28

52

 

Negative

29

64

 

EMVI

   

0.450

Positive

26

60

 

Negative

31

56

 

The neoadjuvant–surgery interval (day)

   

0.002

 < 84

25

79

 

 ≥ 84

32

37

 

The types of surgical procedures

   

0.303

Dixon

48

104

 

Others

9

12

 
  1. Clinical TNM stage, according to the eighth edition of the AJCC staging manual
  2. CEA carcinoembryonic antigen, CA199 carbohydrate antigen 199, CRM circumferential resection margin, EMVI extramural vascular invasion