Delayed postoperative radiotherapy increases the incidence of radiographic local tumor progression before radiotherapy and leads to poor prognosis in spinal metastases

Table 2 Patient-reported outcomes

Outcomes	NPBR^a	PBR^a	P-value^b
NRS
Preoperative	6.8 ± 2.2	6.5 ± 2.0	0.469
Follow-up	3.2 ± 2.6	4.2 ± 3.1	0.253
P value^c	< 0.001	0.012
KPS
Preoperative	52.5 ± 17.6	55.0 ± 19.9	0.559
Follow-up	66.8 ± 26.3	55.7 ± 26.8	0.115
P value^c	< 0.001	0.879
Mobility
Preoperative	2.6 ± 1.7	2.9 ± 1.7	0.532
Follow-up	3.0 ± 1.6	2.5 ± 1.8	0.194
P value^c	0.086	0.531
Mobility time (months)
Follow-up	14.1 ± 12.8	8.3 ± 7.4	0.086
Sphincter dysfunction
Preoperative	0.3 ± 0.5	0.1 ± 0.4	0.343
Follow-up	0.1 ± 0.3	0.3 ± 0.5	0.213
P value^c	0.007	0.500

KPS, Karnofsky performance status; NPBR, no progression before radiotherapy; NRS, numeric rating scale; PBR, progression before radiotherapy
^aValues are expressed as mean ± standard deviation
^bComparison between the two groups
^cComparison of preoperative- and follow-up values

ISSN: 1748-717X