Table 3 Changes in tumor volume and dose intensity based on dose volume histogram before and after surgical spacer placement
| Â | Parameter | Preoperative Mean value | Postoperative Mean value | T-test |
|---|---|---|---|---|
Tumor | Volume (ml) | 34.1 | 45.9 | 0.023 |
GTV | V95% (%) | 49.7 | 71.9 | 0.001 |
|  | V60(Gy [RBE]) (%) | 66.4 | 84.7 |  < 0.001 |
|  | D95% (Gy [RBE]) | 49.7 | 53.7 |  < 0.001 |
|  | Dmean (Gy [RBE]) | 61.5 | 64.5 |  < 0.001 |
| Â | Dmin (Gy [RBE]) | 46.2 | 48.1 | 0.019 |
CTV | V95% (%) | 50.8 | 66.7 | 0.004 |
| Â | V60(Gy [RBE]) (%) | 64.1 | 78.4 | 0.002 |
| Â | D95% (Gy [RBE]) | 48.0 | 50.1 | 0.005 |
| Â | Dmean (Gy [RBE]) | 61.4 | 63.6 | 0.003 |
| Â | Dmin (Gy [RBE]) | 44.6 | 45.2 | 0.030 |
PTV | V95% (%) | 39.3 | 52.8 | 0.005 |
| Â | V60(Gy [RBE]) (%) | 51.1 | 65.2 | 0.002 |
| Â | D95% (Gy [RBE]) | 45.3 | 45.9 | 0.021 |
| Â | Dmean (Gy [RBE]) | 48.7 | 61.1 | 0.002 |
| Â | Dmin (Gy [RBE]) | 37.9 | 37.1 | 0.451 |
Stomach | D0.5Â cc (Gy [RBE]) | 46.6 | 45.8 | 0.190 |
| Â | V48(Gy [RBE]) (cc) | 0.211 | 0.16 | 0.144 |
| Â | V40(Gy [RBE]) (cc) | 22.3 | 12.2 | 0.018 |
| Â | V30(Gy [RBE]) (cc) | 40.0 | 27.5 | 0.038 |
Small intestine | D0.5Â cc (Gy [RBE]) | 47.5 | 47.1 | 0.239 |
| Â | V48(Gy [RBE]) (cc) | 0.331 | 0.3 | 0.337 |
| Â | V40(Gy [RBE]) (cc) | 11.9 | 9.99 | 0.031 |
| Â | V30(Gy [RBE]) (cc) | 21.1 | 16.8 | 0.020 |
Large intestine | D0.5Â cc (Gy [RBE]) | 20.7 | 14.0 | 0.228 |
| Â | V48(Gy [RBE]) (cc) | 0.068 | 0.0008 | 0.101 |
| Â | V40(Gy [RBE]) (cc) | 4.23 | 0.12 | 0.088 |
| Â | V30(Gy [RBE]) (cc) | 8.29 | 0.4 | 0.089 |