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Table 4 Comparison of adverse events between the elective nodal irradiation (ENI) and non-ENI groups

From: Invasion of the pterygoid plates: an indicator for regional lymph node failure in maxillary sinus cancer

CTCAE v4.0 Non-ENI group (n = 38) ENI group (n = 17) p-value
Grade 1/2
no. (%)
Grade 3
no. (%)
Grade 4
no. (%)
Grade 5
no. (%)
Grade 1/2
no. (%)
Grade 3
no. (%)
Grade 4
no. (%)
Grade 5
no. (%)
Acute toxicities          
 All toxicities ≥ Grade 3   23 (61)     9 (53)    0.8
 Mucositis, oral 24 (63) 12 (32) 11 (65) 5 (29) 1
 Cheilitis 3 (8)  
 Radiation-induced dermatitis 21 (55) 2 (4) 5 (29) 1 (6) 1
 Conjunctivitis 13 (34) 5 (29)  
 Keratitis 3 (8) 1 (3) 1 (6) 1
 Nausea 4 (11) 1 (6) 1
 Anorexia 3 (8) 1 (6) 0.5
 Pneumonitis 2 (5) 1 (3) 1 (6) 1
 Depression 1 (3) 1
 Injury to the carotid artery 1 (6) 1
 Transient ischemic attacks 1 (3) 1
Late toxicities          
 All toxicities > Grade 3   5 (13)     7 (41)    0.03
 Epiphora 5 (13) 3 (18)  
 Dry eye 2 (5)  
 Cataract 2 (6) 2 (5) 1 (6) 1
 Optic nerve disorders 2 (5) 1
 Dysesthesia 6 (16) 2 (12)  
 Trismus 1 (3) 2 (12) 0.2
 Osteonecrosis of the jaw 1 (6) 1 (6) 0.3
 Anorexia 1 (6) 0.3
 Pneumonitis 2 (12) 0.09
 Stroke 1 (3)