Skip to main content

Table 1 Patient and treatment characteristics

From: Phase I trial of dose-escalated stereotactic radiosurgery (SRS) boost for unfavorable locally advanced oropharyngeal cancer

Characteristic

No. of patients (%) (N = 34)

Age (mean)

60 years

Smoking history (median)

35 pack-years

Gender

 

 Male

27 (79%)

 Female

7 (21%)

AJCC 7th edition Stage

 

 III

3 (9%)

 IVa

28 (82%)

 IVb

3 (9%)

AJCC 8th edition stage

 

 II (P16 positive)

17 (50%)

 III (P16 positive)

4 (12%)

 III (p16 negative)

3 (9%)

 IVa (p16 negative)

10 (29%)

T Classification

 

 T1

2 (6%)

 T2

15 (44%)

 T3

11 (32%)

 T4a

5 (15%)

 T4b

1 (3%)

N Classification

 

 N0

1 (3%)

 N1

5 (15%)

 N2a

5 (15%)

 N2b

14 (41%)

 N2c

9 (26%)

Primary site

 

 Tonsil

19 (56%)

 Base of tongue

13 (38%)

 Pharyngeal wall

1 (3%)

 Soft palate

1 (3%)

Mean boost volume

54 cc (range 13–185 cc)

 8 Gy SRS boost

11 (32%)

 10 Gy SRS boost

16 (47%)

 5 Gy × 2 SRS boost

7 (21%)

HPV status

 

 HPV-positive smokers

21 (62%)

 HPV-negative

13 (38%)

Chemotherapy

 

 Cisplatin

27 (79%)

 Cetuximab

1 (3%)

 Carboplatin paclitaxel

1 (3%)

 Cisplatin followed by carboplatin and paclitaxel

4 (12%)

 Unknown

1 (3%)