Target/OAR | Parameter | Initial composite plan | Revised phase II only | ||
---|---|---|---|---|---|
3-fraction combined | 7-fraction combined | Phase I Dose 8 Gy/1 fraction | Phase I Dose 20 Gy/5 fractions | ||
Spinal cord | Maximum PRV Point Dose | 23 Gy | 32 Gy | 15 Gy | 12 Gy |
Sacral nerve roots | Maximum point dose | 26 Gy | 32 Gy | 26 Gy | 32 Gy |
Kidneys | Mean Whole Kidney Dose | 6 Gy | 6 Gy | 6 Gy | 6 Gy |
Maximum point dose | 26 Gy | 26 Gy | 26 Gy | 26 Gy | |
Esophagus | Maximum point dose | 25.5 Gy | 35 Gy | 20 Gy | 15 Gy |
Small Bowel | Maximum point dose | 27 Gy | 32 Gy | 20 Gy | 15 Gy |
Stomach | Maximum point dose | 30 Gy | 35 Gy | 20 Gy | 15 Gy |
Large Bowel | Maximum point dose | 34.5 Gy | 40 Gy | 20 Gy | 15 Gy |
Trachea | Maximum point dose | 30 Gy | 40 Gy | 20 Gy | 15 Gy |
Liver | Mean whole liver | 8–9 Gy | 8–9 Gy | 8 Gy | 8 Gy |
Dose per volume | D700cc < 17.1 Gy | D700cc < 21 Gy | D700cc < 17 Gy | D700cc < 21 Gy | |
Lung | Dose per Volume | V11Gy < 37% | V13.5 Gy < 37% | V11 Gy < 37% | V13.5 Gy < 37% |