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Table 3 Univariate analysis for local control

From: Hypofractionated proton beam radiotherapy in patients with unresectable liver tumors: multi-institutional prospective results from the Proton Collaborative Group

Variable

Level

HR

95% CI

P

Age

 

1.02

0.97–1.08

0.35

ECOG

1–3 v 0

2.50

0.29–21.80

0.41

Prior treatment

Yes vs. No

0.53

0.10–2.81

0.45

Tumor size (cm)

 

0.87

0.65–1.17

0.36

Fractionation

15/25 vs. 5

0.39

0.07–1.99

0.26

BED, GyE ± 

 

0.97

0.93–1.00

0.057

  1. ECOG Eastern Cooperative Oncology Group performance status, BED biological equivalent dose, HR hazard ratio, GyE Gy equivalent
  2.  ± BED considered as a continuous variable. The HR represents the effect of an increase of 1 GyE