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Table 1 Patient characteristics and correlation between the mean platelet volume and patient and treatment characteristics

From: The decreased mean platelet volume is associated with poor prognosis in patients with oropharyngeal cancer treated with radiotherapy

Parameter

N (%)

MPV, median (mean ± SD)

p value

Sex

 Male

244 (76.5%)

10.30 (10.23 ± 1.17)

0.618

 Female

75 (23.5%)

10.20 (10.35 ± 1.15)

 

Age at diagnosis

 < 60

168 (52.7)

10.20 (10.22 ± 1.27)

0.432

 > 60

151 (47.3%)

10.30 (10.30 ± 1.04)

 

Smoking status

 Former or never

121 (37.9%)

10.30 (10.22 ± 1.18)

0.673

 Current

191 (59.9%)

10.30 (10.27 ± 1.16)

 

 Missing data

7 (2.2%)

  

Alcohol consumption

 Former or never

189 (59.2%)

10.40 (10.37 ± 1.13)

0.009

 Current

114 (35.7%)

10.10 (10.03 ± 1.18)

 

 Missing data

16 (5%)

  

HPV status

 Negative

23 (7.2%)

10.00 (9.94 ± 1.15)

0.110

 Positive

37 (11.6%)

10.50 (10.43 ± 0.89)

 

 Missing data

259 (81.2%)

  

Tumor grade

   

 G 1/2

135 (42.3%)

10.20(10.24 ± 1.12)

0.270

 G 3/4

180 (56.4%)

10.40 (10.28 ± 1.21)

 

 Missing data

4 (1.3%)

  

Tumor stage

 T 1/2

116 (36.4%)

10.30 (10.24 ± 1.29)

0.518

 T 3/4

197 (61.8%)

10.20 (10.24 ± 1.20)

 

 Missing data

6 (1.9%)

  

Nodal involvement

 N0

34 (10.7%)

10.40 (10.35 ± 1.06)

0.694

 N+

281 (88.1%)

10.30 (10.25 ± 1.18)

 

 Missing data

4 (1.3%)

  

Surgery

 Yes

140 (43.9%)

10.40 (10.28 ± 1.27)

0.275

 No

179 (56.1%)

10.20(10.25 ± 1.09)

 

Induction chemotherapy

   

 Yes

63 (19.7%)

10.30 (10.27 ± 0.95)

0.882

 No

256 (80.3%)

10.30 (10.26 ± 1.22)

 

Concomitant chemotherapy

 Yes

87 (27.3%)

10.05 (9.97 ± 1.61)

0.141

 No

232 (72.7%)

10.30 (10.37 ± 0.94)

 

Chemo-/immunotherapy

 No

86 (26.9%)

10.05 (9.97 ± 1.61)

0.338

 Erbitux

38 (11.9%)

10.35 (10.38 ± 1.05)

 

 Cisplatin

194 (60.8%)

10.30 (10.37 ± 0.92)

 

RTx technique

 3D conformal

144 (45.1%)

10.30 (10.24 ± 1.37)

0.684

 IMRT

175 (54.9%)

10.20 (10.28 ± 0.97)

 

RTx total dose (Gy)

 ≤ 60

61 (19.1%)

10.2 (10.35 ± 1.05)

0.779

 > 60 to < 70

75 (23.5%)

10.40 (10.20 ± 1.42)

 

 ≥ 70

183 (57.4%)

10.30 (10.26 ± 1.09)

 
  1. n, number of patients; SD, standard deviation; MPV, mean platelet volume; IMRT, intensity modulated radiation therapy