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Table 2 Comparison of the dose–volume histograms

From: Risk factors for osteoradionecrosis of the jaw in patients with head and neck squamous cell carcinoma

Characteristic   V10 (%) V20 (%) V30 (%) V40 (%) V50 (%) V60 (%) V70 (%)
ORNJ
No  Median 92.90 86.59 76.61 65.07 41.68 12.16 0.03
Yes  Median 93.99 90.29 84.16 73.48 61.37 35.31 3.22
   p value* 0.4050 0.2340 0.0148 0.0016 < 0.0001 < 0.0001 0.0041
RT technique
3D-CRT  Median 87.57 81.37 76.07 70.47 52.84 26.62 0.21
IMRT  Median 99.42 92.92 79.39 53.95 27.30 5.33 0.00
   p value* < 0.0001 < 0.0001 0.6300 < 0.0001 < 0.0001 < 0.0001 0.0001
Primary tumor site
OPC/OC  Median 95.04 90.24 83.21 73.87 56.26 32.03 0.00
Others  Median 88.99 82.00 69.43 57.59 32.86 3.98 1.19
   p value* < 0.0001 < 0.0001 < 0.0001 < 0.0001 < 0.0001 < 0.0001 < 0.0001
  1. *Mann–Whitney U test
  2. V10, V20, V30, V40, V50, V60, and V70, represent relative volumes of the jaw exposed to 10, 20, 30, 40, 50, 60, and 70 Gy, respectively
  3. ORNJ, osteoradionecrosis of the jaw; RT, radiation therapy; 3D-CRT, 3-dimensional conformal radiation therapy; IMRT, intensity-modulated radiation therapy; OPC, oropharyngeal cancer; OC, oral cancer