Table 1 Clinical and treatment characteristics of the sample
From: Severity of radiation pneumonitis, from clinical, dosimetric and biological features: a pilot study
Characteristics | |
|---|---|
No. of patients | 16 |
Sex | |
Male | 14 (87.5%) |
Female | 2 (12.5%) |
Age (range) | 63 (58.8–76) |
Smoking history | |
Current | 10 (62.5%) |
Former | 5 (31.2%) |
Never | 1 (6.2%) |
Pulmonary function (range) | |
FVC (%) | 101 (87–105.8) |
FEV1 (%) | 85.5 (71.5–93.3) |
FEV1/FVC | 67.9 (60.5–73) |
DLCO (%) | 71 (57.2–87.5) |
Comorbidities | |
Hypertension | 5 (31.2%) |
Diabetes | 3 (18.8%) |
COPD | 11 (68.8%) |
Heart disease | 2 (12.5%) |
Vascular disease | 2 (12.5%) |
Histologic type | |
Adenocarcinoma | 4 (25%) |
Squamous cell carcinoma | 9 (56.2%) |
Large cell neuroendocrine carcinoma | 2 (12.5%) |
NSCLC | 1 (6.2%) |
Location | |
Mediastinum | 1 (6.2%) |
Hilar | 3 (18.8%) |
Right upper lobe | 6 (37.5%) |
Right inferior lobe | 2 (12.5%) |
Left superior lobe | 3 (18.8%) |
Left inferior lobe | 1 (6.2%) |
Radiation doses (range) | |
Mean dose (Gy) | 17.2 (12.7–22.9) |
V20 (%) | 30 (20.3–35.8) |
V5 (%) | 60 (47.5–65.8) |
Pneumonitis grades | |
1 | 5 (31.3%) |
2 | 5 (31.3%) |
3 | 5 (31.3%) |
4 | 0 (0%) |
5 | 1 (6.1%) |