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Table 2. Mean DVH metrics for HA-WBRT in current study compared to NRG CC001 constraints.

From: Automated contouring and planning pipeline for hippocampal-avoidant whole-brain radiotherapy

 

NRG CC001

 

Per protocol

Acceptable variation

Current study

Mean (range)

PTV D2% (Gy)

< 37.5

37.5–40

34.3 (33.3–37.2)

PTV D98% (Gy)

> 25

22.5–25

26.5 (25.3–28.8)

PTV V30Gy (%)

> 95

90–95

95 (95–95)

Hippocampus D100% (Gy)

< 9

9–10

8.1 (7.4–9.1)

Hippocampus Dmax (Gy)

< 16

16–17

13.1 (9.7–15.7)

Optic Nerves Dmax (Gy)

< 30

30–37.5

29.8 (25.4–32.3)

Optic Chiasm Dmax (Gy)

< 30

30–37.5

30.1 (29.0–32.0)

  1. D dose, PTV planning target volume