Table 2 Summary estimated of diagnostic performance of the ⁶⁸Ga-PSMA PET/CT for lymph node staging in patient with Prostate Cancer

Budaus [25]

30

33

0

67

100

11

Herlemann [20]

34

91

33

9

67

10

Maurer [24]

130

66

1

34

99

11

Gupta [22]

12

100

20

0

80

10

Obek [21]

51

53

14

47

86

10

Van Leeuwen [26]

30

64

5

62

94

11

Zhang [12]

42

93

4

7

96

9

Van Leeuwen [2]

140

60

12

40

88

10

Yilmaz [23]

24

38

6

62

94

10

Yaxley [13]

208

38

6

62

94

11

Pooled analysis

Inconsistency (I²) (95% CI)

99% (98–99)

Sample Size

701

SEN^e (95% CI)

0.84 (0.55, 0.95)

SPE^f (95% CI)

0.95 (0.87, 0.98)

PLR^g (95% CI)

17.2 (6.3, 47.2)

NLR^h (95% CI)

0.17 (0.05, 0.56)

DORⁱ (95% CI)

100 (18, 545)

Youden Index

0.79