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Table 4 Univariate and multivariate Cox regression analyses for factors affecting the time to local tumor control

From: Efficacy and safety of CyberKnife radiosurgery in elderly patients with brain metastases: a retrospective clinical evaluation

 

Univariate Analyses

Multivariate Analysis

HR

95% CI

p-value

HR

95% CI

p-value

Age

1.136

1.048–1.231

0.002

1.135

1.028–1.258

0.012

Sex (male)

0.247

0.092–0.662

0.005

0.270

0.100–0.730

0.010

PTV

1.186

1.051–1.339

0.006

1.128

0.996–1.277

0.058

Prescribed dose*

0.732

0.498–1.074

0.111

   

Primary tumor

1.025

0.902–1.166

0.703

   

GPA class

1.266

0.633–2.530

0.505

   
  1. HR Hazard ratio, CI Confidence interval, PTV Planning target volume, GPA Graded prognostic assessment. *for the prescribed dose only single fractions were included. bold text: p ≤ 0.05 was regarded as significant