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Table 1 Baseline characteristics

From: Acute toxicity of normofractionated intensity modulated radiotherapy with simultaneous integrated boost compared to three-dimensional conformal radiotherapy with sequential boost in the adjuvant treatment of breast cancer

 

All patients (446)

Arm A (230) IMRT/SIB

Arm B (216) 3D-CRT/seqB

 

Age (median)

55.7

56.0

55.3

p = 0.44

Tumor stage

 pT1–2

368 (82.5%)

189 (82.1%)

179 (82.9%)

p = 0.29

 pT3–4

7 (1.6%)

5 (2.2%)

2 (0.9%)

 

 cT1–2

69 (15.5%)

34 (14.8%)

35 (16.2%)

p = 0.16

 cT3–4

2 (0.4%)

2 (0.4%)

0

 

Nodal stage

 pN0

295 (66.1%)

155 (67.4%)

140 (64.8%)

p = 0.55

 pN1–3

80 (33.9%)

39 (32.6%)

41 (35.2%)

 

 cN0

50 (11.2%)

23 (10.0%)

27 (12.5%)

p = 0.22

 cN+

21 (4.7%)

13 (5.7%)

8 (3.7%)

 

Regional nodal irradiation

66 (14.8%)

28 (12.2%)

38 (17.6%)

p = 0.11

Chemotherapy

   

p = 0.99

 adjuvant

194 (43.5%)

100 (43.5%)

94 (43.5%)

 

 neoadjuvant

71 (36.6%)

36 (36.0%)

35 (37.2%)

 
  1. IMRT intensity-modulated radiotherapy, SIB simultaneous integrated boost, seqB sequential boost